Shrinkage of the Heart in Anesthetized, Thoracotomized Dogs

Author:

RUSHMER ROBERT F.1

Affiliation:

1. Department of Physiology and Bio-physics, University of Washington, School of Medicine, Seattle, Wash

Abstract

Changes in heart size have been studied by means of intraventricular gages, serial roentgenography and cinefluorographic angiocardiography. Evidence is presented that the area of the cardiac silhouette and the area and diameter of the left ventricle all diminish in response to thoracotomy and during recovery return toward the pre-operative dimensions. Since fundamental concepts of cardiac function and control are based largely on investigation of exposed hearts, these concepts must be re-examined in intact, unanesthetized animals and man.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

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