Author:
Lawner P M,Oldendorf W H,Braun L D
Abstract
A method is described for measurement of cerebral blood flow utilizing the washout of microwave delivered heating. Using a microwave source attenuated to achieve a brain temperature elevation of 0.5-0.75 degrees C after a 2 second exposure in the rat, cerebral blood flow was calculated from the temperature washout curve monitored by a small thermistor implanted in the brain. The results obtained with this method were comparable to those obtained using the [14C] butanol method. To our knowledge this represents the first description of a method to deliver a blood flow "indicator" atraumatically directly into brain tissue.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology
Reference23 articles.
1. The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations;Kety S;Am J Physiol,1945
2. THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES 1
3. Regional blood flow by fractional distribution of indicators;Sapirstein LA;Am J Physiol,1958
4. A Thermoelectric Blood Flow Recorder in the Form of a Needle
5. Internal calorimetry in the determination of thermal conductivity and blood flow;Grayson J;J Physiol,1952
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