1. From the Department of Medicine (Y.W., J.H., L.Z., K.M., R.E.P., V.J.D.), Duke University School of Medicine, Durham, NC; and Department of Medicine (Y.W., J.E.I., L.Z., K.M., C.-C.L., R.E.P., V.J.D.), Brigham & Women’s Hospital and Harvard Medical School, Boston, Mass.