1. From the Departments of Molecular Physiology (S.S., M. Sato, S.M., F.N., T.K., N.T.-I., K.M., Y.M., S. Kobayashi) and Neurosurgery (S.S., S. Kashiwagi, T.K., M. Suzuki), Yamaguchi University School of Medicine, Ube, Japan; and the Research Center of Mochida Pharmaceutical Co, LTD (S. Kuriyama, K.H.), Gotemba, Japan.