1. From the Cardiology Division and the Vascular Biology Group, Department of Medicine (E.D.M., X.W., A.N., B.T., K.H., J.R.B.D., A.H., G.H., S.L.A.), the Division of Cardiac Surgery (I.R.), the Cardiovascular Research Group (A.B.), and the Department of Physiology (S.L.A.), University of Alberta, Alberta, Canada.