Regulation of Ion Channel Expression

Author:

Rosati Barbara1,McKinnon David1

Affiliation:

1. From the Departments of Physiology and Biophysics (B.R.) and Neurobiology and Behavior (D.M.), Institute of Molecular Cardiology, State University of New York at Stony Brook, Stony Brook, NY.

Abstract

A potentially important mechanism controlling ion channel expression is homeostatic regulation, which can act to maintain a stable electrophysiological phenotype in cardiac myocytes as well as to provide plasticity in response to genetic, pathological, or pharmacological insults. The capabilities and limitations of the homeostatic regulatory mechanisms that contribute to the control of cardiac ion channel expression are the primary topic of this review.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

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