Is the Failing Heart Energy Starved?-Reference-Cited by-同舟云学术

Is the Failing Heart Energy Starved?

Published:2004-07-23 Issue:2 Volume:95 Page:135-145
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

Ingwall Joanne S.¹,Weiss Robert G.¹

Affiliation:

1. From Brigham and Women’s Hospital (J.S.I.), Harvard Medical School, Boston, Mass; and Johns Hopkins Hospital and University School of Medicine (R.G.W.), Cardiology Division, Baltimore, Md.

Abstract

The requirement of chemical energy in the form of ATP to support systolic and diastolic work of the heart is absolute. Because of its central role in cardiac metabolism and performance, the subject of this review on energetics in the failing heart is ATP. We briefly review the basics of myocardial ATP metabolism and describe how this changes in the failing heart. We present an analysis of what is now known about the causes and consequences of these energetic changes and conclude by commenting on unsolved problems and opportunities for future basic and clinical research.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.0000137170.41939.d9

Reference103 articles.

1. MYOCARDIAL METABOLISM IN CONGESTIVE HEART FAILURE

2. Myocardial metabolism in congestive heart failure

3. Metabolic remodelling of the failing heart: the cardiac burn-out syndrome?

4. IS THE FAILING HEART ENERGY DEPLETED?

5. American Heritage Dictionary of the English Language 3rd ed. Boston MA: Houghton Mifflin Co; 1992.

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