1. From the Departments of Genomics Sciences (W.Q., J.J.G.), Cardiovascular & Metabolic Diseases (E.G.M., B.R.B., A.E.R.), Global Medical Affairs (R.R.), and Global Toxicology (E.A.G.B.), Pfizer, Inc, St Louis, Mo, and Prince Henry’s Institute of Medical Research (J.W.F.), Clayton, Victoria, Australia.