1. From the US/MRC Centre for Molecular and Cellular Biology (J.M.-S., W.d.L., V.C.), University of Stellenbosch, Tygerberg, South Africa; and the Department of Cardiovascular Medicine (E.F., Z.L., C.R., H.W.), University of Oxford, Oxford, UK. Present address for Z.L. is the Department of Cardiology, Fourth Military Medical University, Xi’an City, People’s Republic of China.