1. From the Departments of Physiology and Medicine and the Cardiovascular Research Laboratories (S.A.H., J.I.G., J.M.S., T.H., C.M., A.N., C.C., D.A.N., M.C.J., J.S.F., K.P.R., R.S.R., K.D.P.), David Geffen School of Medicine at the University of California, Los Angeles; and the Department of Cell Biology (M.R.R., M.F.), The Scripps Research Institute, La Jolla, Calif. Present affiliation for R.S.R. is the Department of Medicine, University of California, San Diego School of Medicine.