1. From the Department of Biochemical Genetics (M.T.-A., S.K.), Medical Research Institute, Department of Internal Medicine (H.I., S.A., M.H., F.M.), Section of Molecular embryology (P.S., M.-A.I.), and Cardiothoracic Surgery (M. Shimizu, J.K., M. Sunamori), Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.