1. From the Department of Pharmacology (B.J.K., S.G.S., H.D., A.E.G., T.S., J.C.M., M.M.), Georgetown University Medical Center, Washington, DC; the Department of Cardiology and Angiology (P.K., L.F.), University Hospital Münster, Germany; and the Department of Molecular and Cellular Pharmacology (J.D.P.), University of Miami School of Medicine, Miami, Fla.