1. From the Institute for Medicine and Engineering (Y.F., E.H., P.F.D., I.L.), Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia; Department of Medicine (E.R.M., H.O., S.M.H., R.L.W.), Cardiovascular Division, Section of Vascular Medicine, University of Pennsylvania, Philadelphia; and Department of Pediatrics (G.H.R.), The Children’s Hospital of Philadelphia, Pennsylvania.