1. From the Departments of Biochemistry (J.O., X.W., S.C., C.F.-P.), Pediatrics (T.O., G.L.), Pharmacology (G.L.), Physiology (Z.K.), School of Molecular and Systems Medicine (J.O., X.W., S.C., T.O., G.L., Z.K., C.F.-P.), and the Cardiovascular Research Group (J.O., X.W., S.C., T.O., G.L., Z.K., C.F.-P.), University of Alberta, Edmonton, Alberta, Canada.