1. From the Departments of Epidemiology (M.L.P.P., S.S.M., V.J.A.V., A.H., S.A.S., M.A.I.), Neurology (M.L.P.P., P.J.K., M.A.I.), and Radiology (M.A.I.), Erasmus MC University Medical Center, Rotterdam, The Netherlands; and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA (A.H.).