1. From the Cardiovascular Research Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada (E.O’D., J.M.G.); and Department of Medicine, Division of Cardiology, University Health Network at Mount Sinai Hospital (J.M.G., S.M., H.M., B.L.M, J.S.F.), and Department of Medicine, Division of Cardiology at the Women’s College Hospital (P.J.H.), University of Toronto, Ontario, Canada.