Twenty-Four–Hour Central (Aortic) Systolic Blood Pressure: Reference Values and Dipping Patterns in Untreated Individuals-Reference-Cited by-同舟云学术

Twenty-Four–Hour Central (Aortic) Systolic Blood Pressure: Reference Values and Dipping Patterns in Untreated Individuals

Published:2022-01 Issue:1 Volume:79 Page:251-260
ISSN:0194-911X
Container-title:Hypertension
language:en
Short-container-title:Hypertension

Author:

Weber Thomas¹^ORCID,Protogerou Athanase D.²,Agharazii Mohsen³,Argyris Antonis²^ORCID,Aoun Bahous Sola⁴,Banegas Jose R.⁵^ORCID,Binder Ronald K.¹,Blacher Jacques⁶,Araujo Brandao Andréa⁷,Cruz Juan J.⁵,Danninger Kathrin¹,Giannatasio Cristina⁸,Graciani Auxiliadora⁵,Hametner Bernhard⁹^ORCID,Jankowski Piotr¹⁰^ORCID,Li Yan¹¹,Maloberti Alessandro⁸^ORCID,Mayer Christopher C.⁹¹²,McDonnell Barry J.¹³^ORCID,McEniery Carmel M.¹,Antonio Mota Gomes Marco¹⁴^ORCID,Machado Gomes Annelise¹⁴^ORCID,Lorenza Muiesan Maria¹⁵^ORCID,Nemcsik Janos¹⁶,Paini Anna¹⁵,Rodilla Enrique¹⁷,Schutte Aletta E.¹⁸¹⁹²⁰,Sfikakis Petros P.²,Terentes-Printzios Dimitrios²¹^ORCID,Vallée Alexandre⁶,Vlachopoulos Charalambos¹²²^ORCID,Ware Lisa²³,Wilkinson Ian¹²,Zweiker Robert¹,Sharman James E.¹^ORCID,Wassertheurer Siegfried⁹,

Affiliation:

1. Cardiology Department, Klinikum Wels-Grieskirchen, Austria (T.W., R.K.B., K.D.).

2. Cardiovascular Prevention and Research Unit, Clinic-Laboratory of Pathophysiology and First Department of Propeadeutic Internal Medicine, Laiko Hospital, Medical School, National and Kapodistrian University of Athens, Greece (A.D.P., A.A., P.P.S.).

3. Centre de Recherche Du CHU de Québec, Université Laval, Canada (M.A.).

4. Lebanese American University School of Medicine, Byblos, Lebanon (S.A.B.).

5. Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPAZ and CIBER in Epidemiology and Public Health, Spain (J.R.B., J.J.C., A.G.).

6. AP-HP Centre-Université de Paris, Hôpital Hôtel-Dieu, Centre de diagnostic et de thérapeutique, France (J.B., A.V.).

7. State University of Rio de Janeiro, Brazil (A.A.B.).

8. School of Medicine and Surgery, Milano-Bicocca University and Cardiology 4, ASST GOM Niguarda, Milan, Italy (C.G., A.M.).

9. Austrian Institute of Technology, Vienna, Austria (B.H., C.C.M., S.W.).

10. Institute of Cardiology, Jagellonian University, Krakow, Poland (P.J.).

11. Centre for Vascular Evaluations, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (Y.L.).

12. Experimental Medicine and Immunotherapeutics, Addenbrooke’s Hospital, University of Cambridge, United Kingdom (C.M.M., I.W.).

13. Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, United Kingdom (B.J.M.).

14. Centro Universitario CESMAC, Alagoas, Brazil (M.A.M.G., A.M.G.).

15. Department of Clinical and Experimental Sciences, Centro per la Prevenzione e Cura dell’ipertensione Arteriosa, University of Brescia and ASST Spedali Civili, Italy (M.L.M., A.P.).

16. Department of Family Medicine, Semmelweis University, Budapest, Hungary (J.N.).

17. Universidad Cardenal Herrera-CEU, CEU Universities, Hospital de Sagunto, Valencia, Spain (E.R.).

18. School of Population Health, University of New South Wales, Sydney, Australia (A.E.S.).

19. The George Institute for Global Health, Sydney, Australia (A.E.S.).

20. Hypertension in Africa Research Team, SAMRC Unit for Hypertension and Cardiovascular Disease, North-West University, South Africa (A.E.S.).

21. First Department of Cardiology, Hippokration General Hospital, National and Kapodistrian University of Athens, Greece (D.T.-P., C.V.).

22. SAMRC/Wits Developmental Pathways for Health Research Unit, South Africa (L.W.).

23. DSI-NRF Centre of Excellence in Human Development, University of the Witwatersrand, South Africa (L.W.).

Abstract

Central (aortic) systolic blood pressure (cSBP) is the pressure seen by the heart, the brain, and the kidneys. If properly measured, cSBP is closer associated with hypertension-mediated organ damage and prognosis, as compared with brachial SBP (bSBP). We investigated 24-hour profiles of bSBP and cSBP, measured simultaneously using Mobilograph devices, in 2423 untreated adults (1275 women; age, 18–94 years), free from overt cardiovascular disease, aiming to develop reference values and to analyze daytime-nighttime variability. Central SBP was assessed, using brachial waveforms, calibrated with mean arterial pressure (MAP)/diastolic BP (cSBP MAP/DBPcal ), or bSBP/diastolic blood pressure (cSBP SBP/DBPcal ), and a validated transfer function, resulting in 144 509 valid brachial and 130 804 valid central measurements. Averaged 24-hour, daytime, and nighttime brachial BP across all individuals was 124/79, 126/81, and 116/72 mm Hg, respectively. Averaged 24-hour, daytime, and nighttime values for cSBP MAP/DBPcal were 128, 128, and 125 mm Hg and 115, 117, and 107 mm Hg for cSBP SBP/DBPcal , respectively. We pragmatically propose as upper normal limit for 24-hour cSBP MAP/DBPcal 135 mm Hg and for 24-hour cSBP SBP/DBPcal 120 mm Hg. bSBP dipping (nighttime-daytime/daytime SBP) was −10.6 % in young participants and decreased with increasing age. Central SBP SBP/DBPcal dipping was less pronounced (−8.7% in young participants). In contrast, cSBP MAP/DBPcal dipping was completely absent in the youngest age group and less pronounced in all other participants. These data may serve for comparison in various diseases and have potential implications for refining hypertension diagnosis and management. The different dipping behavior of bSBP versus cSBP requires further investigation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Internal Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.121.17765

Reference64 articles.

1. Does Radial Artery Pressure Accurately Reflect Aortic Pressure?

2. Central blood pressure: current evidence and clinical importance

3. Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors

4. Central Blood Pressure Measurements and Antihypertensive Therapy

5. Association of Central Versus Brachial Blood Pressure With Target-Organ Damage

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Associations of 24‐Hour Central Systolic Blood Pressure With Multiorgan Damage in Nondialysis Patients With Chronic Kidney Disease;Journal of the American Heart Association;2024-08-20

2. 24-h central haemodynamics and cardiovascular outcomes: is calibration the key?;Journal of Hypertension;2024-08-01

3. Chronobioethics: Symphony of biological clocks observed by 7-day/24-hour ambulatory blood pressure monitoring and cardiovascular health;Biomedical Journal;2024-06

4. Another step forward in the introduction of aortic systolic blood pressure assessment into clinical practice?;Hypertension Research;2024-05-21

5. Association of 24-h central hemodynamics and stiffness with cardiovascular events and all-cause mortality. The VASOTENS Registry;Journal of Hypertension;2024-05-15