1. From the Department of Physiology and Functional Genomics (J.Z., M.K.R.), McKnight Brain Institute, University of Florida, Gainesville, FL; Department of Physiology (H.W.), Wakayama Medical University School of Medicine, Kimiidera, Wakayama City, Japan; School of Physiology and Pharmacology (J.F.R.P.), Bristol Heart Institute, University of Bristol, Bristol, United Kingdom.