Primary Aldosteronism: Where Are We Now? Where to From Here?-Reference-Cited by-同舟云学术

Primary Aldosteronism: Where Are We Now? Where to From Here?

Published:2022-04 Issue:4 Volume:79 Page:726-735
ISSN:0194-911X
Container-title:Hypertension
language:en
Short-container-title:Hypertension

Author:

Funder John W.¹^ORCID,Carey Robert M.¹^ORCID

Affiliation:

1. Hudson Institute of Medical Research, Monash University, Clayton, Victoria, Australia. Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville.

Abstract

Primary aldosteronism, the most common secondary form of hypertension, is thought to be present in ≈5% to 10% of hypertensive adults. However, recent studies indicate that its prevalence may be at least 3-fold higher based on the identification of renin-independent (autonomous) aldosterone production that is not suppressible with dietary sodium loading in a large fraction of adults with primary hypertension. Currently, the screening rate for primary aldosteronism in adults with primary hypertension is <1%. This review summarizes current thinking about primary aldosteronism from the standpoint of 3 key questions: Where are we now? Where to from here? So how do we get there?

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Internal Medicine

Reference41 articles.

1. K + Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension

2. Prevalence, Clinical, and Molecular Correlates of KCNJ5 Mutations in Primary Aldosteronism

3. Somatic Mutations Affecting the Selectivity Filter of KCNJ5 Are Frequent in 2 Large Unselected Collections of Adrenal Aldosteronomas

4. Microarray, qPCR, andKCNJ5Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors

5. Effect ofKCNJ5Mutations on Gene Expression in Aldosterone-Producing Adenomas and Adrenocortical Cells

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Primary aldosteronism with hypokalemic rhabdomyolysis: a case report and review of the literature;Journal of Medical Case Reports;2024-08-09

2. Primary Aldosteronism and Risk of Cardiovascular Outcomes: Genome‐Wide Association and Mendelian Randomization Study;Journal of the American Heart Association;2024-08-06

3. Problems of diagnosis and treatment of Connshing syndrome;Clinical Medicine (Russian Journal);2024-07-26

4. Establishment of a scoring model for predicting clinical outcomes in patients with unilateral primary aldosteronism after superselective adrenal artery embolization;Irish Journal of Medical Science (1971 -);2024-06-10

5. Primary aldosteronism: An underdiagnosed clinical entity;Journal of Current Cardiology;2024-05