1. From the Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Science Center at Houston, TX (Y.Z., B.Y., J.A.N., E.B.); Metabolon Inc, Durham, NC (D.A.); Department of Medicine, University of Mississippi Medical Center, Jackson, MS (T.H.M.); Department of Epidemiology, University of North Carolina at Chapel Hill, NC (G.H.); and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX (E.B.).