Release of activatable kallikrein by isolated rat kidneys.-Reference-Cited by-同舟云学术

Release of activatable kallikrein by isolated rat kidneys.

Published:1981-11 Issue:6_pt_2 Volume:3 Page:
ISSN:0194-911X
Container-title:Hypertension
language:en
Short-container-title:Hypertension

Author:

Corthorn J,Roblero J

Abstract

Rat isolated kidneys were perfused for 60 minutes with a modified Krebs-Henseleit bicarbonate solution. Perfusate and urine samples showed kininogenase activity (active kallikrein) which could be enhanced by activation with trypsin (activatable kallikrein). Identification of the kininogenase activity generated by trypsin was made with rat renal kallikrein antiserum, aprotinin, lima bean trypsin inhibitor (LBTI), soybean trypsin inhibitor (SBTI), and ovomucoid. A sample of perfusate was partially purified through DEAD-Sephacel chromatography. Intraarterial injection of this fraction decreased blood pressure in the perfused hind limb of a rat.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Internal Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.HYP.3.6_Pt_2.II-39

Reference12 articles.

1. Webster ME' Kallikrein in glandular tissue in. Handbook of Experimental Pharmacology Bradykinin and Kallikrein edited by Erdos EG Berlin New York Springer 1970 p 131

2. The renal kallikrein-kinin system in human and in experimental hypertension

3. Kallikrein like activity in perfusate and urine of isolated rat kidneys;Roblero J;Am J Physiol,1976

4. Corthorn J Imanan T Yoshida H Kaizu T Pierce JV Pisano JJ Isolation of prokallikrein from human urine In Advances in Experimental Medicine and Biology. Kinins II edited by Fuju S Monya H Suzuki T. New York: Plenum Press 1979 p 575

5. Croxatto HR San Martin M Roblero J. Kallikrein on arterial hypertension Kallikrein-hke activity in the urine of figure-ineight ligature in one kidney Advan Exp Med Biol 21:457 1972

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. VARIATIONS IN KALLIKREIN-LIKE ESTERASE ACTIVITY IN DIFFERENT SEGMENTS OF THE RAT NEPHRON DURING SALT-LOAD AND SALT-DEPLETION;Acta Pathologica Microbiologica Scandinavica Series A :Pathology;2009-08-15

2. Bradykinin B 2 -Receptor Activation Augments Norepinephrine Exocytosis From Cardiac Sympathetic Nerve Endings;Circulation Research;1997-11

3. Role of perfusate hydrogen ion activity in kallikrein release from isolated rat kidneys;Pflügers Archiv - European Journal of Physiology;1996-06

4. Uterine Kallikrein in the Early Pregnant Rat1;Biology of Reproduction;1993-10-01

5. Polarity of kallikrein release and activation in perfused rat kidneys;American Journal of Physiology-Renal Physiology;1990-11-01