Thrombin Generation in Normal Subjects and Cardiac Patients

Author:

VON KAULLA KURT N.1,VON KAULLA EDITH1

Affiliation:

1. Department of Medicine, University of Colorado School of Medicine, Denver, Colorado

Abstract

A refined, reliable thrombin generation test with good sensitivity for both hypo- and hypercoagulability is described. When serial thrombin generation curves were obtained in cardiac patients subjected to standardized treadmill stress, fluctuations of the clotting system were observed in some and a marked tendency to hypercoagulability in others. The relationship of in vitro hypercoagulability as reflected by thrombin generation to an increased tendency to thrombosis remains to be determined.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference30 articles.

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3. L'emocoagulazione nell'infarto miocardico recente;BARBANO G.;Therapeutikon,1961

4. MARCHAL G. LEROUX M. E. AND SAMAMA M.: Atlas de Thrombodynamographie. Service de Propagande Edit. Inform. Paris.

5. Continuous automatic recordings of fibrin formation and fibrinolysis: A valuable tool for coagulation research;VON KAULLA K. N.;J. Lab. Clin. Med.,1957

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