Effects of Sodium Pentobarbital on Electrical and Reflex Activation of the Cardiovascular System-Reference-Cited by-同舟云学术

Effects of Sodium Pentobarbital on Electrical and Reflex Activation of the Cardiovascular System

Published:1964-03 Issue:3 Volume:14 Page:228-235
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

PEISS CLARENCE N.¹,MANNING JOHN W.¹

Affiliation:

1. Departments of Physiology, Stritch School of Medicine, Loyola University, Chicago, Illinois, and Emory University, Atlanta, Georgia

Abstract

The effects of small doses of sodium pentobarbital (5 mg/kg) on the cardiovascular responses to stimulation of the medulla, hypothalamus, stellate ganglia and sciatic nerve, and to bilateral occlusion of the carotid arteries were studied. It was concluded that: 1) this drug depressed cardiovascular responses to all of these procedures except stimulation of the stellate ganglia; 2) the effects of the anesthetic in this dose are referable to some part(s) of the central nervous system; 3) cardiovascular responses to hypothalamic stimulation were depressed more than those elicited by stimulation of the dorsal medullary reticular formation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.14.3.228

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