Simple Scoring System to Predict In‐Hospital Mortality After Surgery for Infective Endocarditis

Author:

Gatti Giuseppe1,Perrotti Andrea2,Obadia Jean‐François3,Duval Xavier45,Iung Bernard67,Alla François8,Chirouze Catherine9,Selton‐Suty Christine10,Hoen Bruno11,Sinagra Gianfranco1,Delahaye François3,Tattevin Pierre12,Le Moing Vincent1213,Pappalardo Aniello1,Chocron Sidney2,Duval X.,Alla F.,Bouvet A.,Briancon S.,Cambau E.,Celard M.,Chirouze C.,Danchin N.,Doco‐ Lecompte T.,Delahaye F.,Etienne J.,Iung B.,Le Moing V.,Obadia J. F.,Leport C.,Poyart C.,Revest M.,Selton‐Suty C.,Strady C.,Tattevin P.,Vandenesch F.,Bernard Y.,Chocron S.,Chirouze C.,Hoen B.,Plesiat P.,Abouliatim I.,De Place C.,Tattevin P.,Revest M.,Donnio P. Y.,Alla F.,Carteaux J. P.,Doco‐Lecompte T.,Lion C.,Aissa N.,Selton‐Suty C.,Baehrel B.,Jaussaud R.,Nazeyrollas P.,Strady C.,Vernet V.,Cambau E.,Duval X.,Iung B.,Nataf P.,Chidiac C.,Celard M.,Delahaye F.,Obadia J. F.,Vandenesch F.,Aumaître H.,Frappier J. M.,Le Moing V.,Oziol E.,Sotto A.,Sportouch C.,Poyart C.,Bouvet A.,Vandenesch F.,Celard M.,Bes M.,Abrial E.,Acar C.,Aissa N.,Alexandra J. F.,Amireche N.,Amrein D.,Andre P.,Appriou M.,Arnould M. A.,Assayag P.,Atoui A.,Aziza F.,Baille N.,Bajolle N.,Battistella P.,Baumard S.,Ben Ali A.,Bertrand J.,Bialek S.,Bois Grosse M.,Boixados M.,Borlot F.,Bouchachi A.,Bouche O.,Bouchemal S.,Bourdon J. L.,Bouvet A.,Brasme L.,Bricaire F.,Brochet E.,Bruntz J. F.,Cady A.,Cailhol J.,Caplan M. P.,Carette B.,Carteaux J. P.,Cartry O.,Cazorla C.,Celard M.,Chamagne H.,Champagne H.,Chanques G.,Chastre J.,Chevalier B.,Chirouze C.,Chocron S.,Chometon F.,Christophe C.,Cohen A.,Colin de Verdiere N.,Danchin N.,Daneluzzi V.,David L.,De Lentdecker P,Delahaye F.,Delcey V.,Deleuze P.,Donal E.,Duval X.,Deroure B.,Descotes‐Genon V.,Didier Petit K.,Dinh A.,Doat V.,Duchene F.,Duhoux F.,Dupont M.,Ederhy S.,Epaulard O.,Evest M.,Faucher J. F.,Fantin B.,Fauveau E.,Ferry T.,Fillod M.,Floch T.,Fraisse T.,Frapier J. M.,Freysz L.,Fumery B.,Gachot B.,Gallien S.,Gandjbach I.,Garcon P.,Gaubert A.,Genoud J. L.,Ghiglione S.,Godreuil C.,Grentzinger A.,Groben L.,Gherissi D.,Guéret P.,Hagege A.,Hammoudi N.,Heliot F.,Henry P.,Herson S.,Hoen B.,Houriez P.,Hustache‐Mathieu L.,Huttin O.,Imbert S.,Iung B.,Jaureguiberry S.,Kaaki M.,Konate A.,Kuhn J. M.,Kural Menasche S.,Lafitte A.,Lafon B.,Lanternier F.,Le Chenault V.,Le Moing V.,Lechiche C.,Lefèvre‐Thibaut S.,Lefort A.,Leguerrier A.,Lemoine J.,Lepage L.,Leport C.,Lepouse ́ C.,Leroy J.,Lesprit P.,Letranchant L.,Loisance D.,Loncar G.,Lorentz C.,Mabo P.,Magnin‐Poull I.,May T.,Makinson A.,Man H.,Mansouri M.,Marxcon O.,Maroni J. P.,Masse V.,Maurier F.,Meyohas M. C.,Michel P. L.,Michelet C.,Mechaï F.,Merceron O.,Messika‐Zeitoun D.,Metref Z.,Meyssonnier V.,Mezher C.,Micheli S.,Monsigny M.,Mouly S.,Mourvillier B.,Nallet O.,Nataf P.,Nazeyrollas P.,Noel V.,Obadia J. F.,Oziol E.,Papo T.,Payet B.,Pelletier A.,Perez P.,Petit J. S.,Philippart F.,Piet E.,Plainvert C.,Popovic B.,Porte J. M.,Pradier P.,Ramadan R.,Revest M.,Richemond J.,Rodermann M.,Roncato M.,Roigt I.,Ruyer O.,Saada M.,Schwartz J.,Selton‐Suty C.,Simon M.,Simorre B.,Skalli S.,Spatz F.,Strady C.,Sudrial J.,Tartiere L.,Terrier De La Chaise A.,Thiercelin M. C.,Thomas D.,Thomas M.,Toko L.,Tournoux F.,Tristan A.,Trouillet J. L.,Tual L.,Vahanian A.,Verdier F.,Vernet Garnier V.,Vidal V.,Weyne P.,Wolff M.,Wynckel A.,Zannad N.,Zinzius P. Y.,

Affiliation:

1. Cardiovascular Department, University Hospital of Trieste, Italy

2. Department of Thoracic and Cardiovascular Surgery, EA3920, University Hospital Jean Minjoz, Besançon, France

3. Cardiology Hospital Louis Pradel, Hospices Civils, Lyon, France

4. IAME, Inserm UMR 1137, University Paris Diderot Sorbonne Paris Cité, Paris, France

5. Inserm Clinical Investigation Center 1425, Paris, France

6. Department of Cardiology, AP‐HP, Bichat Hospital, Paris, France

7. DHU Fire, Paris, France

8. EA 4003, University of Nancy, France

9. Department of Infective and Tropical Diseases, University Hospital Jean Minjoz, Besançon, France

10. Department of Cardiology, University Hospital of Nancy, France

11. Department of Infective and Tropical Diseases, University Hospital of Pointe à Pitre, France

12. Department of Infective and Tropical Diseases, University Regional Hospital, Rennes, France

13. UMI 233, Institute of Development Research, University of Montpellier, France

Abstract

Background Aspecific scoring systems are used to predict the risk of death postsurgery in patients with infective endocarditis ( IE ). The purpose of the present study was both to analyze the risk factors for in‐hospital death, which complicates surgery for IE , and to create a mortality risk score based on the results of this analysis. Methods and Results Outcomes of 361 consecutive patients (mean age, 59.1±15.4 years) who had undergone surgery for IE in 8 European centers of cardiac surgery were recorded prospectively, and a risk factor analysis (multivariable logistic regression) for in‐hospital death was performed. The discriminatory power of a new predictive scoring system was assessed with the receiver operating characteristic curve analysis. Score validation procedures were carried out. Fifty‐six (15.5%) patients died postsurgery. BMI >27 kg/m 2 (odds ratio [ OR ], 1.79; P =0.049), estimated glomerular filtration rate <50 mL/min ( OR , 3.52; P <0.0001), New York Heart Association class IV ( OR , 2.11; P =0.024), systolic pulmonary artery pressure >55 mm Hg ( OR , 1.78; P =0.032), and critical state ( OR , 2.37; P =0.017) were independent predictors of in‐hospital death. A scoring system was devised to predict in‐hospital death postsurgery for IE (area under the receiver operating characteristic curve, 0.780; 95% CI, 0.734–0.822). The score performed better than 5 of 6 scoring systems for in‐hospital death after cardiac surgery that were considered. Conclusions A simple scoring system based on risk factors for in‐hospital death was specifically created to predict mortality risk postsurgery in patients with IE .

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

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