1. From the Faculty of Science, Institute of Cardiovascular Research, Royal Holloway College, University of London (ICR2UL), London, United Kingdom (M.S.K., P.S.); Department of Medicine, Ashford and St Peters Hospital, London, United Kingdom (M.S.K., P.S); and Department of Neuroscience, Imperial College Cerebrovascular Research Unit (ICCRU), London, United Kingdom (T.B., M.S.K., O.H., P.B., P.S.).