1. From the Division of Health and Social Care Research, King’s College London, London, United Kingdom (I.J.M., Y.W., C.M., A.G.R., C.D.A.W.); and National Institute for Health Research Comprehensive Biomedical Research Centre at Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom (Y.W., A.G.R., C.D.A.W.).