Effect of Upper Limb Botulinum Toxin Injections on Impairment, Activity, Participation, and Quality of Life Among Stroke Patients

Author:

Caty Gilles D.1,Detrembleur Christine1,Bleyenheuft Corinne1,Deltombe Thierry1,Lejeune Thierry M.1

Affiliation:

1. From the Université catholique de Louvain (G.D.C., C.D., C.B., T.M.L.), Cliniques universitaires Saint-Luc, Physical Medicine and Rehabilitation Department, Brussels, Belgium; and the Université catholique de Louvain (T.D.), Cliniques universitaires de Mont-Godinne, Physical Medicine and Rehabilitation Department, Yvoir, Belgium.

Abstract

Background and Purpose— The purpose of this study was to study the effect of Botulinum toxin type A (BoNT-A) injections in spastic upper limb muscles on impairment, activity, participation and quality of life in chronic stroke patients. Methods— BoNT-A (Dysport) was injected into several upper limb spastic muscles in a group of 20 patients. Neurological impairment (muscle tone and strength, dexterity, SIAS), activity (ABILHAND), participation (SATIS-Stroke), and quality of life (SF36) were assessed before and 2 months after the injections. Results— BoNT-A injections improved muscle tone, but had no impact on dexterity, manual ability, social participation, and quality of life. Conclusions— In this study, BoNT-A injections in spastic upper limbs significantly reduced neurological impairments, but had no functional impact.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology

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