1. From the Division of Clinical Neurosciences (M.B., P.A.G.S., F.M.C., J.M.W.), University of Edinburgh, Western General Hospital, Edinburgh, UK; Servizio Aziendale per le Malattie Cerebrovascolari (G.C., E.R.), Ospedale BG Villa, Citta’ della Pieve, Italy; Radiology Department (N.A.), Western General Hospital, Edinburgh, UK; Department of Public Health & Epidemiology (J.J.D.), University of Birmingham, UK.