1. From the Institute for Ageing and Health (D.G.J., S.A.M., M.I.T.) and the Institute for Cellular Medicine (D.G.J., S.A.M., L.R., G.A.F., M.I.T.), Newcastle University, Newcastle upon Tyne, UK; and the Cardiology Department (L.-B.T.), Leeds General Infirmary, Leeds, UK.