1. From the Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada (C.R., J.C.); Departments of Neurology and Neurosurgery (C.R.) and Epidemiology and Biostatistics (C.R.), McGill University, Montréal, Québec, Canada; and Center for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, United Kingdom (C.R., L.L., A.G., L.S., P.M.R.).