Affiliation:
1. Division of Otolaryngology, Emory University School of Medicine, Atlanta, Georgia 30322
Abstract
Dogs breathed one of four gas mixtures (5% CO
2
-95% O
2
, 5% CO
2
-95% air, 10% CO
2
-90% O
2
, and 10% CO
2
-90% air) for as long as two hours. Regional cerebral blood flow as well as flow in nasal, otic, pituitary and skin tissue were measured by means of 15 ± 5 µ radioactively labeled microspheres. The normal values for cerebral blood flow and arterial blood gases were very similar to those of other investigators. Inhalation of CO
2
induced an increase in cerebral blood flow that was significantly higher than is usually reported. Increases varied from 100% (with 5% CO
2
-95% air) to 250% (with 10% CO
2
-90% O
2
). Blood flow in the temporal bone behaved much like that of brain in response to CO
2
. In most instances, the pituitary gland blood flow did not increase with inhalation of CO
2
.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology
Reference13 articles.
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