Studies on the Control of Hypertension by Hyphex

Author:

SCHROEDER HENRY A.1,MORROW JOHN D.1,PERRY H. MITCHELL1

Affiliation:

1. From the Hypertension Division, Department of Internal Medicine, Washington University School of Medicine, and Barnes Hospital, St. Louis, Mo.

Abstract

This report is the first of a series on a method for treatment of hypertension by oral hexamethonium chloride and hydrazinophthalazine. When strictly followed blood pressure was maintained at reasonable or normal levels in 80 per cent of 258 cases of severe hypertension. The malignant stage, when present, was reversed. Renal insufficiency and severe cerebral atherosclerosis limit the effectiveness of the method for prolongation of life.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference13 articles.

1. The effect of 1-hydrazinophthalazine and hexamethonium on hypertension;SCHROEDER H. A.;J. Lab. & Clin. Med.,1951

2. CONTROL OF HYPERTENSION BY HEXAMETHONIUM AND 1-HYDRAZINOPHTHALAZINE

3. Further observations on the control of hypertension by Hyphex;SCHROEDER H. A.;J. Lab. & Clin. Med.,1952

4. Pathogenesis of hypertension

5. 7PERRY H. M. JR. MORROW J. D. AND SCHROEDER H. A.: Studies on the control of hypertension by Hyphex. III. Chemical and pharmacological observations. (To be published.)

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