Effect of Anticoagulants on Experimental Cerebral Infarction

Author:

WHISNANT JACK P.1,MILLIKAN CLARK H.1,SAYRE GEORGE P.1,WAKIM KHALIL G.1

Affiliation:

1. From the Mayo Clinic and the Mayo Foundation, Rochester, Minn.

Abstract

Cerebral infarction is attended by extravasation of blood in varying degrees. The present study was undertaken to learn whether anticoagulant therapy increases the extravasation and thereby diminishes or negates possibly favorable therapeutic effects. A series of experiments on dogs is described and the clinical implications are discussed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference12 articles.

1. ANTICOAGULANT THERAPY IN CEREBRAL VASCULAR DISEASE—CURRENT STATUS

2. The effect of dieumarol on the heart in experimental acute coronary occlusion;BLUMGART H. L.;Tr. A. Am. Physicians,1947

3. MOYES P. D. MILLIKAN C. H. WAKIm K. G. SAYRE G. P. AND WHISNANT J. P.: Influence of anticoagulants on experimental canine cerebral infarets. Proc. Staff Meet. Mayo Clin. 32: 124 1957.

4. Relationship Between Anticoagulants and Hemorrhagic Cerebral Infarction in Experimental Animals

5. Influence of anticoagulants on cerebral infaretion produced by homologous blood clots. Proe. Staff Meet;FRAZIER S. H.;Mayo Clin.,1957

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