Affiliation:
1. From the Department of Physiology, University of Berne, Berne, Switzerland.
Abstract
The contributions made during the past 10 years are reviewed. Intracellular recording has made it possible to state absolute values for the cardiac resting potential (90 mv., inside negative to outside) and the "overshoot" during activity (30 mv., inside positive to outside). The surface membrane of a resting fiber is considered to be predominately permeable to K ions. During activity, Na conductance increases and K conductance decreases. The latter process is thought to be essential for explaining the high membrane resistance that is measured during the long-lasting "plateau" found with cardiac muscle. A hypothesis is presented that would account for the termination of the plateau and the beginning of repolarization.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference20 articles.
1. The normal membrane potential of frog sartorius fibers
2. Membrane Resting and Action Potentials of Single Cardiac Muscle Fibers
3. CORABOEUF E. AND WEIDMANN S.: Potentiels d'action du muscle cardiaque obtenus A l'aide de microelectrodes intracellulaires: Presence d'une inversion de potentiel. Compt. rend. Soc. biol. 143: 1360 1949.
4. Elektrophysiologie des Herzens bei einphasischer Ableitung
5. WEIDMANN S.: Elektrophysiologie der Herzmuskelfaser. Berne and Stuttgart Huber 1956.
Cited by
17 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献