Glucose Blockage of the Increase in Stroke Volume Produced by Smoking

Abstract

The percentage changes in the cardiac output, stroke volume, and heart rate were determined in seven healthy habitual smokers after smoking, after glucose, and after smoking preceded by glucose. No significant changes occur after glucose. There is a significant increase in cardiac output, stroke volume, and heart rate after smoking. Pretreatment with glucose did not change the heart-rate response to smoking. Nevertheless, the cardiac-output response was diminished. This decrease is due to a block in the increase in stroke volume induced by smoking.