Affiliation:
1. From the Department of Medicine, Division of Cardiovascular Disease and the Cardiovascular Laboratory, Duke University Medical Center, Durham, North Carolina.
Abstract
The clinical features of 16 patients with primary pulmonary hypertension are reviewed. Repeated cardiac catheterizations at intervals of 1 to 4 years during the course of the disease were performed in five patients. In three of the five patients there was a progressive increase in pulmonary artery pressure, total pulmonary resistance, and a decline in cardiac output. In two patients the pulmonary hemodynamics remained unchanged between studies at intervals of 2 and 4 years. Arterial oxygen saturation decreased with progression of the disease, presumably reflecting the appearance of an uneven distribution of pulmonary capillary flow. The course of the illness was variable and unaffected by any mode of therapy, including long-term anticoagulation.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference25 articles.
1. Diseases of the Heart and Circulation. Ed. 2. Philadelphia;P.;J. B. Lippincott Company,1956
2. Preoperative Evaluation of a Continuous Murmur in the Chest
3. In Intravascular Catheterization, H. A. Zimmerman, Ed. Springfield, Illinois;MOTLEY H. L.;Charles C Thomas,1959
4. Primary pulmonary hypertension
5. Idiopathic pulmonary hypertension: Etiology, pathogenesis, diagnosis and treatment
Cited by
58 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献