Cation Exchange Resin in the Treatment of Congestive Heart Failure

Author:

ELKINTON J. R.1,SQUIRES R. D.1,KLINGENSMITH W. C.1

Affiliation:

1. From the Chemical Section and the Edward B. Robinette Foundation of the Department of Medicine, and Hospital of the University of Pennsylvania, Philadelphia, Pa.

Abstract

Electrolyte balances were measured in four edematous cardiac patients receiving cation exchange resin. It was found that such therapy would increase the fecal loss of sodium and, in some of the cases, would result in the loss of edema which had been refractory to other forms of therapy. In these cases the main route of sodium excretion was through the kidneys and not through the intestinal tract. The resin appeared to potentiate the renal action of simultaneously administered mercurial diuretics.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference20 articles.

1. Sodium depletion as a therapeutic procedure: The value of ion-exchange resins in withdrawing sodium from the body;DOCK W.;Tr. A. Am. Physicians,1946

2. Biochemical and clinical effects of cationic exchange resin;COBBEY T. S.;Federation Proc.,1949

3. THE EFFECT OF A CATION EXCHANGE RESIN ON ELECTROLYTE BALANCE AND ITS USE IN EDEMATOUS STATES

4. Observations on the administration of ammonium cation exchange resin to patients with cardiac edema;CURRENS J. H.;J. Clin. Investigation,1950

5. Carboxylic cation exchange resin studies in animals and humans;DANOWSK;J. Clin. Investigation,1950

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