Author:
Harrison L,Gallagher J J,Kasell J,Anderson R H,Mikat E,Hackel D B,Wallace A G
Abstract
A cryosurgical instrument was used to ablate atrioventricular conduction. The procedure was carried out in 20 dogs and subsequently in three patients with drug resistant, life-threatening supraventricular tachycardias. In patients, the cryosurgical unit lowered the temperature of the His bundle area to 0 degrees C, effecting complete but reversible heart block. Rewarming resulted in resumption of normal atrioventricular conduction. The His bundle region then was cooled to -60 degrees C; complete heart block was produced with two or more 90-120 second freezes. Postoperative evaluations revealed persistent atrioventricular conduction block. The lesion showed no tendency to rupture, form aneurysm, or interfere with valvular function. In the clinical cases, postoperative studies demonstrated a stable pacemaker arising proximal to the branching portion of the His bundle. A potential application of the cryosurgical technique might be ablation of sites of dysrhythmia (i.e., ectopic foci, re-entry circuits, accessory pathways).
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference29 articles.
1. Therapeutic uses of cardiac pacing in tachyarrhythmias. In His Bundle Electrocardiography and Clinical Electrophysiology, edited by Narula OS. Philadelphia;Barold SS;F A Davis,1975
2. The treatment of complete heart block by the combined use of a myocardial electrode and an artificial pacemaker;Weirich WL;Surg Forum,1957
3. Therapeutic Surgical Division of the Human Conduction System
4. Le traitement chirurgical des acces de tachycardie paroxystique graves du syndrome de Wolff-Parkinson et ses limites;Latour H;Arch Mal Coeur,1970
Cited by
187 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献