Abstract
A case is described in which nifedipine, a new coronary vasodilator, was effective in relieving attacks of Prinzmetal's angina unresponsive to conventional therapy. The extreme frequency of the anginal attacks provided evidence that lower doses of nifedipine lost their effectiveness approximately 4 hours after administration. A month after initiation of nifedipine, nitrates were withdrawn since they had been ineffective in controlling the attacks. A myocardial infarction occurred immediately, presumably due to coronary spasm.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference13 articles.
1. Angina pectoris I. A variant form of angina pectoris
2. Coronary Arterial Spasm in Prinzmetal Angina
3. Dihydropyridine, eine neue Gruppe stark wirksamer Coronartherapeutika
4. Hosada S Kimura E: In Proceedings First International Nifedipine (Adalat) Symposium Tokyo 1973. Editors: K Haschimoto E Kimura T Kobayashi. Tokyo University of Tokyo Press 1974 p 175
5. Grun G Fleckenstein A: Die elektromechanische Entkoppelung det glatten Gefassmuskulatur als Grundprinzip det Coronardilatation durch 4-(2'-nitrophenyl)-2 6-dimethy1-1 4-dihydropyridine-3 5-dicarbosaure-di
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