Nonrheumatic Mitral Insufficiency

Author:

KLUGHAUPT MARTIN1,FLAMM M. D.1,HANCOCK E. WILLIAM1,M.D. DONALD C. HARRISONN1

Affiliation:

1. From the Cardiology Division, Department of Medicine, Stanford University School of Medicine, Palo Alto, California.

Abstract

Twenty patients with mitral insufficiency (MI) due to ruptured chordae tendineae, papillary muscle infarction, or left ventricular enlargement with no organic disease of the mitral valve have been studied during the past 3 years. Nineteen had valve replacement, and one had plastic repair of ruptured chordae tendineae; all have been followed from 6 months to 3 years. Preoperative data were different in those who were improved by surgery (13 patients) and those who were not (seven patients). The group in which good results were obtained had a short history of heart failure, little or no evidence of left atrial (LA) enlargement in the electrocardiograms and x-rays, and striking LA ν waves at catheterization. In the group demonstrating poor results, heart failure was of longer duration, gross four-chamber cardiomegaly was present, and LA ν waves were only moderate. Thus, patients with nonrheumatic mitral insufficiency with high-pressure LA regurgitant waves and only moderate LA enlargement are likely to benefit from mitral valve surgery, even when the primary cardiovascular disease is hypertension, arteriosclerosis, or a cardiomyopathy. These patients generally have ruptured chordae tendineae.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Cited by 25 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The underlying causes of chordae tendinae rupture: A systematic review;International Journal of Cardiology;2010-08

2. Acute Mitral Regurgitation: Physiological and Pharmacological Considerations in the Management of a Critically Ill Patient;Anaesthesia and Intensive Care;1992-08

3. Chordal rupture: Repair or replacement?;Recent Progress in Mitral Valve Disease;1984

4. Aortic stenosis and rupture of mitral chordae tendineae;Journal of the American College of Cardiology;1983-04

5. Current status of radionuclide imaging in valvular heart disease;The American Journal of Cardiology;1980-12

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