Studies on the Effect of Oral and Parenteral Administration of Visammin (Khellin) in Patients with Angina Pectoris

Author:

SCOTT RALPH C.1,IGLAUER ARNOLD1,GREEN ROBERT S.1,KAUFMAN JOSEPH W.1,BERMAN BERNARD1,MCGUIRE JOHNSON1

Affiliation:

1. From the Cardiac Laboratory, Department of Internal Medicine, College of Medicine, University of Cincinnati and the Cincinnati General Hospital, Cincinnati, Ohio.

Abstract

Of 20 carefully studied patients with angina pectoris given oral visammin, 4 had a significant reduction in number of pains. Eleven stated that their pains were less severe and less easily precipitated while taking visammin. There was questionable improvement in the exercise tolerance test in 2 of 9 patients after oral visammin therapy. The daily oral dose ranged from 40 mg. to 240 mg. Undesirable side effects were encountered in 17 of the 20 patients. Parenteral administration of visammin was evaluated by means of the ballistocardiograph, the exercise tolerance test, and by tilting.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference24 articles.

1. Visammin as generic designation for dimethoxYmethyl-furano-chromone;J. A. M. A.,1949

2. AMMI VISNAGA IN THE TREATMENT OF THE ANGINAL SYNDROME

3. Comparative pharmacology of khellin;KILLAMI K. F.;Federation Proc.,1950

4. The coronary vasodilator action of khellin

5. KHELLIN IN ANGINA PECTORIS

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