Discrete Subaortic Stenosis Complicated by Aortic Valvular Regurgitation

Author:

MORROW ANDREW G.1,FORT LYNN1,ROBERTS WILLIAM C.1,BRAUNWALD EUGENE1

Affiliation:

1. From the Clinic of Surgery and Cardiology Branch National Heart Institute, Bethesda, Maryland.

Abstract

Four patients are described in whom combined aortic stenosis and regurgitation was evident on examination. In each of them obstruction to left ventricular outflow was shown to be due to congenital subaortic stenosis, and aortic regurgitation resulted from the sequelae of bacterial endocarditis. The presence of this unusual combination of congenital and acquired malformations was suggested by certain clinical findings, and results of the preoperative hemodynamic and angiographic studies that established the diagnosis are presented. In three patients the subaortic membrane was resected, and aortic regurgitation was corrected by reconstruction or replacement of the aortic valve. All of the patients evidenced striking clinical improvement after operation, confirmed by the results of postoperative hemodynamic assessments. A fourth patient died before operation; the pathologic findings are presented in detail.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference12 articles.

1. Determination of Fraction of Left Ventricular Volume Ejected per Beat and of Ventricular End-Diastolic and Residual Volumes

2. Cusp replacement and coronary artery perfusion in open operations on the aortic valve;BAHNSON H. T.;Ann. Surg.,1960

3. FONTANA R. S. AND EDWARDS J. E.: Congenital cardiac disease: A review of 357 cases studied pathologically. Philadelphia and London W. B. Saunders Co. 1962.

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