Affiliation:
1. From the Department of Cardiology, Division of Medicine, City of Hope Medical Center, Duarte, California.
Abstract
In 20 patients studied by cardiac catheterization, the time required for the diastolic left atrioventricular pressure difference to fall to half its initial value (half-time) varied with the anatomic severity of the valvular stenosis. In mild mitral stenosis, the half-time was approximately 100 msec; in moderate stenosis, it was about 200 msec; and it was 300 msec or longer in severe stenosis. The half-time at the nonstenotic mitral valve was less than 25 msec.
Although exercise increased the atrioventricular pressure gradient, heart rate, and cardiac output significantly, the half-time was affected only slightly. Mitral regurgitation of various severities did not affect the half-time. The half-time appears to vary inversely with the anatomic orifice area of the mitral valve. The determination of the half-time obviates the need for the commonly used exercise test for the evaluation of mitral stenosis.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference6 articles.
1. Evaluation of the Severity of Mitral Stenosis and Regurgitation
2. Catheterization of the left heart through the interatrial septum: A new technique and its experimental evaluation;JR.;Surg Forum,1958
3. Simplified Calculation of Cardiac Output From Dye Dilution Curves Recorded by Oximeter
4. Hydraulic formula for calculation of the area of the stenotic mitral valve, other cardiac valves, and central circulatory shunts. I
5. Dynamics and consequences of stenosis or insufficiency of the cardiac valves. In Handbook of Physiology, Section 2: Circulation, vol. 1, edited by W. F. Hamilton and P. Dow. Washington, D. C;WERKO L.;American Physiological Society,1962
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