Effective Closure of the Mitral Valve without Atrial Systole

Author:

BRAUNWALD EUGENE1,ROCKOFF S. DAVID1,OLDHAM H. NEWLAND1,ROSS JOHN1

Affiliation:

1. From the Cardiology Branch and the Clinic of Surgery, National Heart Institute, and the Diagnostic X-ray Department, Clinical Center, National Institutes of Health, Bethesda, Maryland.

Abstract

There has been considerable dispute concerning the role of atrial contraction in the closure of the atrioventricular valves. Selective angiocardiograms with left ventricular [see figure in the PDF file] opacification in 43 patients having a variety of arrhythmias that resulted in the absence of atrial systole, or in an abnormal temporal relationship between atrial and ventricular contractions, revealed no evidence of mitral regurgitation. From this observation it is concluded that a properly timed atrial contraction is not always essential for effective closure of the mitral valve in man.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference26 articles.

1. Cardiovascular Sound in Health and Disease. Baltimore;MCKUSICK V. A.;Williams & Wilkins Co.,1958

2. Effect of atrial systole on ventricular pressure and closure of the A-V valves;LITTLE R. C.;Am. J. Physiol.,1951

3. Studies on Starling's Law of the Heart

4. The transport function of the atrium

5. Influence of atrial contraction and relaxation on closure of the mitral valve;SARNOFF S. J.;Circulation Research,1962

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