A New Method Utilizing Indicator-Dilution Technics for Estimation of Left-to-Right Shunts in Infants

Author:

KROVETZ L. JEROME1,GESSNER IRA H.1

Affiliation:

1. From the Department of Pediatrics and the Cardiovascular Laboratory, J. Hillis Miller Health Center, University of Florida, Gainesville, Florida.

Abstract

The short circulatory pathways of infants cause rapid systemic and pulmonary circulation times. So rapid are they that the usual methods for calculating left-to-right shunts frequently yield a considerable overestimation. A new formula was described for use with injections into the left heart and arterial sampling. This formula applied to 11 infants and 7 older patients showed a significantly better correlation with oximetric calculations than did the right heart injections. This method also will reveal the presence of a left-to-right shunt that is of insufficient magnitude to distort dye curves obtained following right heart injections.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference9 articles.

1. Studies on the circulation. I. Injection method: Physical and mathematical considerations;KINSMAN J. M.;Am. J. Physiol.,1929

2. GESSNER I. H. KROVETZ L. J. STENGER V. PRYSTOWSKY H. BENSON R. W. AND EITz-MAN D. V.: Determination of left ventricular output in the human newborn in first two hours of life. Abstracts of the 34th Annual Meeting of the Society for Pediatric Research Seattle Washington June 18-20 1964 p. 35.

3. Estimation of left to right shunts from arterial dilution curves;CARTER S. A.;J. Lab. & Clin. Med.,1960

4. Dye Dilution Curves in Cyanotic Congenital Heart Disease

5. A new type of syringe holder for performance of indicator-dilution curves

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