Measurement of Central Venous Oxygen Saturation in Patients with Myocardial Infarction

Author:

GOLDMAN ROBERT H.1,KLUGHAUPT MARTIN1,METCALF THOMAS1,SPIVACK ALFRED P.1,HARRISON DONALD C.1

Affiliation:

1. From the Division of Cardiology, Stanford University School of Medicine, and the Palo Alto-Stanford Hospital Coronary Care Unit.

Abstract

Central venous oxygen saturation (CVSO 2 ) was measured in 31 patients with myocardial infarction. CVSO 2 correlated well with the patients' clinical course. In those patients not in heart failure, mean ± sem for CVSO 2 was 70 ± 1%. When heart failure was present, CVSO 2 averaged 56 ± 1%. When both heart failure and shock were present, CVSO 2 averaged 43 ± 1%. In nine patients, serial determinations of arterial oxygen saturation and CVSO 2 were made. In 22 of 26 instances, either a fall in CVSO 2 was accompanied by an increase in the arteriovenous oxygen saturation difference or an increase in CVSO 2 was accompanied by a decrease in arteriovenous oxygen saturation difference. Serial measurements of CVSO 2 appear to be a useful method of monitoring changes in myocardial function in patients with myocardial infarction.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference5 articles.

1. GOLDMAN R. H. BRANIFF B. HARRISON D. C. AND SPAVACK A. P.: Early detection of heart failure by central venous oxygen saturation monitoring. (Abstr.) Amer J Cardiol 21: 100 1967.

2. Spectrophotometric analysis of uncontaminated blood for oxyhemoglobin;CKABEE W. E.;J Lab Clin Med,1955

3. Oxygen saturation of blood in the venae cavae, right heart chambers, and pulmonary vessels of healthy subjects;BARRATT-BOYES B. G.;J Lab Clin Med,1957

4. BLOOD-GAS CHANGES AFTER ACUTE MYOCARDIAL INFARCTION

5. Differences in acid-base levels and oxygen saturation between central venous and arterial blood;WILSON R. F.;Lancet,1967

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