Late Cardiac Complications of Chronic, Severe, Refractory Anemia with Hemochromatosis

Author:

ENGLE MARY ALLEN1,ERLANDSON MARION1,SMITH CARL H.1

Affiliation:

1. From the Divisions of Cardiology and Hematology of the Department of Pediatrics, The New York Hospital-Cornell Medical Center, New York, New York.

Abstract

Four fifths of 49 patients with chronic, severe anemia from birth have manifested, usually during the second decade, signs of hemochromatosis with cardiac involvement. Nineteen patients had 33 attacks of pericarditis. Congestive cardiac failure with arrhythmias developed in 26 patients, and all but one died with this complication. Four others died of sepsis before heart failure was evidenced. Postmortem examination showed hemochromatosis with severe myocardial involvement.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference10 articles.

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2. The role of splenectomy in the management of thalassemia;SMITH C. H.;Blood,1960

3. Cardiac complications of chronic, severe, refractory anemia with hemochromatosis

4. A critical evaluation of the etiology of viral card'tis;KILBOURNE E. D.;New York Heart Association. Conference on Infectious Diseases of the Heart and Circulation.,1963

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