Affiliation:
1. Department of Neurology and Stroke Program University of Michigan Ann Arbor MI USA
2. Institute for Healthcare Policy and Innovation University of Michigan Ann Arbor MI USA
3. Department of Internal Medicine and Cognitive Health Services Research Program University of Michigan Ann Arbor MI USA
4. Department of Epidemiology University of Michigan Ann Arbor MI USA
5. Department of Internal Medicine Wayne State University Detroit MI USA
6. Department of Emergency Medicine University of Michigan Ann Arbor MI USA
Abstract
Background
High blood pressure (BP) increases recurrent stroke risk.
Methods and Results
We assessed hypertension prevalence, treatment, control, medication adherence, and predictors of uncontrolled BP 90 days after ischemic or hemorrhagic stroke among 561 Mexican American and non‐Hispanic White (NHW) survivors of stroke from the BASIC (Brain Attack Surveillance in Corpus Christi) cohort from 2011 to 2014. Uncontrolled BP was defined as average BP ≥140/90 mm Hg at 90 days poststroke. Hypertension was uncontrolled BP or antihypertensive medication prescribed or hypertension history. Treatment was antihypertensive use. Adherence was missing zero antihypertensive doses per week. We investigated predictors of uncontrolled BP using logistic regression adjusting for patient factors. Median (interquartile range) age was 68 (59–78) years, 64% were Mexican American, and 90% of strokes were ischemic. Overall, 94.3% of survivors of stroke had hypertension (95.6% Mexican American versus 92.0% non‐Hispanic White;
P
=0.09). Of these, 87.9% were treated (87.3% Mexican American versus 89.1% non‐Hispanic White;
P
=0.54). Among the total population, 38.3% (95% CI, 34.4%–42.4%) had uncontrolled BP. Among those with uncontrolled BP prescribed an antihypertensive, 84.5% reported treatment adherence (95% CI, 78.8%–89.3%). Uncontrolled BP 90 days poststroke was less likely in patients with stroke who had a primary care physician (adjusted odds ratio [aOR], 0.45 [95% CI, 0.24–0.83];
P
=0.01), greater stroke severity (aOR per‐1‐point‐higher National Institutes of Health Stroke Scale score, 0.96 [95% CI, 0.93–0.99];
P
=0.02), or more depressive symptoms (aOR per‐1‐point‐higher Personal Health Questionnaire Depression Scale‐8 score, 0.95 [95% CI, 0.92–0.99] among those with a history of hypertension at baseline;
P
=0.009).
Conclusions
Greater than one third of survivors of stroke have uncontrolled BP at 90 days poststroke in this population‐based study. Interventions are needed to improve BP control after stroke.
Publisher
Ovid Technologies (Wolters Kluwer Health)