1. From the University of Toledo, Department of Medicine, Toledo, OH (S.T.H., P.B., W.H., C.J.C.); Salford Royal Hospital, Salford, United Kingdom (P.A.K., J.P.R., T.C.); University of Pittsburgh, Department of Statistics, Pittsburgh, PA (H.Y.); and Marshall University, Department of Medicine, Huntington, WV (J.I.S.).