1. From the Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (S.C., D.K.G., B.C., A.M.S., H.S., M.T., S.D.S.); Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD (A.R.S.); and National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD (H.N.).